Télécharger Homocysteine Metabolism: From Basic Science to Clinical Medicine de Ian Graham,Helga Refsum,Irwin H. Rosenberg,Per Magne Ueland Livres Pdf Epub

Télécharger "Homocysteine Metabolism: From Basic Science to Clinical Medicine" de Ian Graham,Helga Refsum,Irwin H. Rosenberg,Per Magne Ueland Francais PDF
Auteur : Ian Graham,Helga Refsum,Irwin H. Rosenberg,Per Magne Ueland
Catégorie : Livres anglais et étrangers,Medicine,Internal Medicine
Broché : * pages
Éditeur : *
Langue : Français, Anglais
In 1962, 30 years after the discovery by du Vigneaud have pathologic consequences. One potentially sig- of a new sulfur amino acid, homocysteine; Carson and nificant health outcome of such mild to moderate Neil reported two siblings with mental retardation in hyperhomocysteinemia is an increased risk of occlu- northern Ireland with elevated urinary homocystine. sive vascular disease. Homocysteine concentrations in Nearly simultaneously, Gerritsen and Waisman patients with vascular disease were, on average, 31 % greater than in normal controls. Prospective assess- identified increased homocystine in the urine of a mentally retarded infant in Wisconsin. Within two ment of vascular disease risk among men with higher years, Harvey Mudd, James Finkelstein, and their homocysteine concentrations indicated that plasma coworkers at the National Institutes of health (USA) homocysteine at only 12% above the upper limit of that the enzyme cystathionine - normal levels was associated with a 3. 4-fold increase had reported synthase was lacking in a liver biopsy specimen from in risk of acute myocardial infarction. Studies from another patient with homocystinuria. This was the original Framingham Heart Study cohort (USA) the first indication of a vitamin relationship to have shown strong, positive correlation between homocystinuria, because that enzyme has as its co- plasma homocysteine concentration and degree of factor vitamin B6 (pyridoxal phosphate). Thereafter, carotid stenosis.
Télécharger Homocysteine Metabolism: From Basic Science to Clinical Medicine de Ian Graham,Helga Refsum,Irwin H. Rosenberg,Per Magne Ueland Livre PDF Gratuit
Treatment of Hypothyroidism - American Family Physician ~ Presented at the International Conference on Homocysteine Metabolism, from Basic Science to Clinical Medicine. Ireland, July 2–5, 1995. Ireland, July 2–5, 1995. Ir J Med Sci .
Emodin Rescued Hyperhomocysteinemia-Induced Dementia and ~ Lowering homocysteine levels with folic acid treatment with or without vitamin B12 has shown few clinical benefits on cognition. Methods: To verify the effect of emodin, a naturally active compound from Rheum officinale, on hyperhomocysteinemia-induced dementia, rats were treated with homocysteine injection (HCY, 400 μg/kg/d, 2 weeks) via vena caudalis.
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